Mark 16:18

Verse 18. They shall take up serpents. When it is necessary for the sake of establishing religion, they shall handle poisonous reptiles without injury: thus showing that God was with him, to keep them from harm. This was literally fulfilled when Paul shook the viper from his hand. See Acts 28:5,6.

Any deadly thing. Any poison usually causing death.

Shall not hurt them. There is a similar promise in Isa 43:2.

They shall lay hands on the sick, etc. See instances of this in the Acts of the Apostles, Acts 3:6,7, 5:15, etc.

(g) "serpents" Lk 10:19, Acts 28:5 (h) "they shall lay" Acts 5:15,16, 28:8, Jas 5:14,15
Copyright information for Barnes